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Biology HL

Chapter 3: DNA and Protein Synthesis

Follow genetic information from faithful DNA copying through transcription, RNA processing and translation, then investigate mutation, gene editing and epigenetic control.

1 simulation entries

Replication fork laboratory

Advance a replication fork and track how the same 5′→3′ rule produces continuous and discontinuous synthesis.

Appears in: 3.1 Semi-conservative DNA Replication, 3.2 Replication Enzymes and Strand Direction, 3.3 DNA Amplification, Profiling and Sequencing, 3.4 Transcription and Gene Activation, 3.5 Translation and the Genetic Code, 3.6 Non-coding DNA and Product Processing, 3.7 Mutation and Protein Consequences, 3.8 Gene Tools, Mutagens and Cancer, 3.9 Gene Regulation and Epigenetics, 3.10 Inheritance, Environment and Expression, 3.11 From DNA Sequence to Regulated Phenotype

Sequence · structure · expression

Genome and expression laboratory

REPLICATION FORK · PARENTAL TEMPLATES IN BLUE / VIOLETfork movement →new leading strand · continuous · 5′→3′ toward forknew lagging strand · RNA primers + Okazaki fragments · 5′→3′ away from forkHELEach daughter duplex contains one parental strand and one newly synthesized strand.