IB Biology HL Theme C: Interaction and interdependence questions

Exam-style multiple choice and written questions with full markschemes. Check multiple choice answers straight away, or type, photograph or draw a written answer and get it marked.

Question 1

Multiple choiceMedium1 mark

A purified enzyme forms a complex with each of four substrates. Shape-change scores compare each molecule’s shape in the complex with its unbound shape; 0 means no change, and a positive score means a change.

SubstrateEnzyme shape-change scoreSubstrate shape-change score
P21
Q20
R01
S00

Which substrate’s results are consistent with induced-fit binding?

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Answer: A. Induced-fit binding involves a change in shape of both the enzyme and the substrate. For P, both shape-change scores are positive, so both molecules change shape during complex formation.
B: uses the enzyme’s positive score but overlooks that the substrate’s score is zero.
C: uses the substrate’s positive score but overlooks that the enzyme’s score is zero.
D: shows no shape change in either molecule and therefore is not induced-fit binding.
Remember: induced-fit binding involves shape changes in both interacting molecules.

Question 2

Multiple choiceMedium1 mark

During aerobic respiration, a 3C pyruvate is processed before its acetyl group enters a cycle containing 4C oxaloacetate. Which description correctly links pyruvate processing to the carbon product and outputs of one cycle turn?

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Answer: D. Oxidative decarboxylation of 3C pyruvate leaves a 2C acetyl group. CoA transfers it to 4C oxaloacetate, forming 6C citrate; Krebs cycle oxidations and decarboxylations yield ATP and reduced NAD while regenerating oxaloacetate. A: gives the link reaction and citrate formation but stops before stating the cycle’s outputs and regeneration of oxaloacetate. B: reverses the redox direction; pyruvate is oxidized, not reduced. C: treats oxaloacetate as a net reactant, rather than a molecule regenerated by the cycle. Remember: acetyl groups enter the Krebs cycle by combining with oxaloacetate, which is then regenerated.

Question 3

Multiple choiceMedium1 mark

After epinephrine is added to a responsive cell, the concentration of cAMP in the cytoplasm rises. Which sequence explains this response?

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Answer: D. Epinephrine binds its transmembrane receptor, which activates a G protein. The activated G protein stimulates adenylate cyclase to produce cAMP inside the cell; cAMP acts as the second messenger that relays the signal to intracellular targets.
A: omits the G protein, incorrectly making the receptor activate adenylate cyclase directly.
B: gives the pathway correctly but misidentifies cAMP as the first messenger; epinephrine is the first messenger.
C: reverses the order of G protein and adenylate cyclase activation.
Remember: the first messenger binds the receptor; the second messenger relays the signal inside the cell.

Question 4

Multiple choiceMedium1 mark

In a neuron, ATP availability is reduced while the membrane remains intact. Assume this affects sodium–potassium pumping only. After sufficient time, which paired change is most likely?

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Answer: C. ATP supplies energy for sodium–potassium pumping, which establishes and maintains ion concentration gradients. With less ATP, pump activity decreases; over time, the gradients weaken and the resting potential becomes less negative.

A: predicts weaker gradients but reverses their effect on the resting potential. B: assumes the pump becomes more active despite reduced ATP availability. D: treats the pump as dissipating, rather than establishing and maintaining, concentration gradients.

Remember: ATP-driven pumping maintains the ion gradients that support the resting potential.

Question 5

Multiple choiceMedium1 mark

A microbial population grows with a fixed supply of the nutrient shown; it is the only limiting resource, and no predators or pathogens are present. As population density rises, which paired identification and population response is expected?

CHOHOHOHHHOHHOHCH₂OH
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Answer: A. The Fischer projection shows an aldehyde at C1 and the characteristic OH arrangement of D-glucose. As population density rises with a fixed supply of the only limiting resource, competition reduces the amount available per individual and slows population growth, tending to return the population towards carrying capacity.

B: reverses the effect of increasing density on the resource available per individual. C: misidentifies glucose as fructose; the displayed structure has a terminal aldehyde group. D: treats a fixed resource supply as density-independent, although its availability per individual changes with population density.

Remember: density-dependent factors tend to counter changes in population size relative to carrying capacity.

Question 6

Multiple choiceMedium1 mark

The diagrams show energy transfers per 100 kJ of chemical energy entering cell respiration in representative autotrophic and heterotrophic cells. Which statement gives the total heat released in each cell type and the stages at which it is released?

Autotrophic cell60 kJ transferred inATP100 kJchemical energyinputCell respirationATP used in cellsCell work:35 kJHeat to environment:40 kJHeat to environment:25 kJHeterotrophic cell70 kJ transferred inATP100 kJchemical energyinputCell respirationATP used in cellsCell work:50 kJHeat to environment:30 kJHeat to environment:20 kJ
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Answer: D. Heat is released at both stages shown, so add the heat outputs for each cell type: autotrophic cells, 40 + 25 = 65 kJ; heterotrophic cells, 30 + 20 = 50 kJ per 100 kJ input.

A: counts only the heat released during cell respiration. B: counts only the heat released when ATP is used. C: gives the totals but reverses the cell-type labels.

Remember: energy transfers are not 100% efficient, including when ATP is produced and when it is used.

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